Spot blotch is caused by Bipolaris sorokinaria & Alternaria triticinia and is a major disease of wheat in warm and humid regions of the world including India, Nepal and Bangladesh. Globally, 40 % of wheat is grown in Indian subcontinent where crop losses are due to Spot blotch which have been estimated in the range of 15-25 %. After monitoring of the disease, it was found that B. sorokinaria dominates in Bihar, Delhi, Rajasthan, Gujarat, Uttar Pradesh, Haryana, Maharashtra and Karnataka whereas A. triticinia is predominantly in Jammu and Kashmir, Himachal Pradesh, Madhya Pradesh and Punjab. Both Alternaria & Bipolaris is causal agent of common rot, seedling blight and black point of wheat. For better understanding of pathogenecity of different fungus on different wheat genotype (Chirya-3, IC-21215, HD-2967, PBW-343, CIANO-T-79, Agralocal and Sonara-64) and the therapeutic potential of medicinal plant extracts (Neem, Henna, Giloy, Bach) against them in order to minimize the loss in yield. So, experiment performed in-vitro condition by isolation of pathogen from affected wheat seed using PDA media and then sub culturing of pathogen on medicinal plant extract to determine the effect of same fungus. The results came out of the experiment were; out of seven genotypes, four genotypes were highly susceptible, two genotypes were resistant and one genotype was highly resistant. In the experiment, triticinia were dominant all over the colonies but their growth in medicinal extracts at 2% concentration was inhibited. 

Key Words: Disease, Seed borne pathogenic fungi, Wheat