ABSTRACT The ecosystem that makes up soil is crucial to the availability of plant nutrients and is home to a wide variety of helpful microorganisms that can be vital to improving soil fertility. Application of compost, vermicompost, and manures are among the soil fertility management techniques for increasing plant nutrients and agricultural productivity. One of the latest promising solutions for addressing the agricultural issues brought on by the still-increasing need for food is the development of phosphate-solubilizing bio-inoculants. In this context, this review will demonstrate the enormous potential of phosphatesolubilizing microorganisms (PSMs) as bio-fertilizers. In low-input agricultural systems, bio-fertilizer technologies can aid in the effective utilization of scarce phosphorus fertilizers and ensure a livable environment. Being aware of and understanding the procedures for isolating and characterizing phosphate-solubilizing microorganisms and the mechanisms by which they solubilized phosphate to make it available for plant nutrition would help strengthen the use of phosphate-solubilizing bioinoculants. In addition, it is important to comprehend the numerous bio-inoculant sources employed for the initial isolation and characterization of native phosphate solubilizers, which will be the focus of this review. This review will also give a thorough overview of the various phosphate solubilization mechanisms and their effects on sustainable agriculture.